IUI Pregnancy: Success rate, Process & Risks

by | Apr 9, 2023 | IUI

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What is IUI?

IUI, or intrauterine insemination, is a fertility treatment that involves the insertion of sperm directly into a woman’s uterus. This procedure increases the chances of sperm reaching the fallopian tubes, where fertilization occurs. IUI is a relatively simple, minimally invasive, and cost-effective method compared to other fertility treatments, such as in vitro fertilization (IVF).


Why is IUI Done?

There are several reasons couples may choose IUI as a fertility treatment:

  • Unexplained Infertility: For couples who have been trying to conceive for a year or more with no success and no identifiable cause, IUI can be a helpful option.
  • Mild Male Factor Infertility: IUI can be beneficial in cases where the male partner has a low sperm count, reduced sperm motility, or poor sperm morphology.
  • Cervical Factor Infertility: If the woman’s cervical mucus is too thick or inhospitable for sperm, IUI bypasses the cervix, increasing the chances of conception.
  • Same-Sex Couples and Single Women: IUI is often the first choice for same-sex female couples or single women using donor sperm.


When is IUI Recommended?

IUI may be recommended in the following situations:

  • Unexplained Infertility: As mentioned earlier, IUI can be a good option for couples who have unexplained infertility.
  • Ovulation Issues: Women who do not ovulate regularly may benefit from IUI combined with fertility medications to stimulate ovulation.
  • Mild Endometriosis: If a woman has mild endometriosis, IUI can help by increasing the chances of sperm reaching the egg.

However, IUI may not be the best option for couples with severe male factor infertility, moderate to severe endometriosis, or damaged or blocked fallopian tubes.


What is IUI Pregnancy?

An IUI pregnancy refers to a successful pregnancy that results from the IUI procedure. Couples may choose to undergo IUI if they are experiencing difficulty conceiving naturally due to various reasons, such as low sperm count, poor sperm motility, or unexplained infertility. IUI is a less invasive and less expensive option compared to other assisted reproductive technologies like in vitro fertilization (IVF). However, the success rates for IUI are generally lower than those for IVF.


Preparing for IUI Pregnancy: Tips and Guidelines

  • Consult a Fertility Specialist: The first step in preparing for IUI is to consult a fertility specialist. They will perform a thorough evaluation to determine if IUI is suitable for your situation and provide personalized guidance on the process.
  • Improve Your Lifestyle: To increase the chances of IUI success, adopt a healthy lifestyle. This includes maintaining a balanced diet, exercising regularly, managing stress, and avoiding tobacco and excessive alcohol consumption.
  • Track Your Menstrual Cycle: Monitoring your menstrual cycle is crucial for IUI success. Familiarize yourself with your cycle and use ovulation predictor kits to help determine your most fertile days.
  • Follow Your Doctor’s Recommendations: Your fertility specialist may prescribe medications to stimulate ovulation or improve sperm quality. It’s essential to follow their recommendations and keep them informed of any side effects or concerns you may have.
  • Prepare Emotionally and Mentally: The IUI journey can be an emotional roller coaster. It’s essential to have a strong support system, including friends, family, or a support group, to help you navigate the process. Don’t hesitate to seek professional help if needed.
  • Communicate with Your Partner: Open communication with your partner is crucial during this time. Share your feelings, concerns, and hopes as you embark on this journey together.


IUI Procedure Step by Step:

The IUI procedure can be broken down into four main stages, each with its own set of steps:

  1. Ovulation Monitoring: The first stage of the IUI process involves monitoring the woman’s menstrual cycle to identify the most fertile days. This can be done using:
  • Ovulation predictor kits
  • Basal body temperature charting
  • Fertility awareness methods
  1. Ovulation Induction (If Needed): If the woman’s ovulation is irregular or absent, fertility medications may be prescribed to stimulate ovulation. The two most common medications include:
  • Clomiphene citrate (Clomid)
  • Gonadotropins (FSH and LH)
  1. Sperm Collection and Preparation: The next step in the IUI process is obtaining a sperm sample from the male partner or a donor. This sample is then processed to isolate the most viable sperm using techniques such as:
  • Swim-up method
  • Density gradient centrifugation
  1. Insemination: The final stage of the IUI procedure involves injecting the prepared sperm into the woman’s uterus. This is done using a thin fine catheter, which is inserted slowly through the cervix and into the uterus. The sperm is then released, and the catheter is removed.


What You Can Expect During the IUI Procedure

During the IUI procedure, you can expect the following:

  • Minimal Discomfort: Most women report minimal discomfort during the insemination process, which is often described as similar to a pap smear.
  • Quick Procedure: The actual insemination takes only a few minutes and can be done in a doctor’s office or fertility clinic.
  • No Anesthesia Required: Since IUI is a minimally invasive procedure, anesthesia is not necessary.


After the IUI Procedure: What’s Next?

After the IUI procedure, there are a few important things to be aware of:

  • Two-Week Wait: You will need to wait for about two weeks before taking a pregnancy test to determine if the IUI was successful. This waiting period can be emotionally challenging, so it’s essential to find ways to manage stress and stay positive.
  • Possible Side Effects: Mild cramping and spotting may occur after the procedure. However, severe pain or heavy bleeding should be reported to your doctor immediately.
  • Follow-Up with Your Doctor: Your doctor will likely schedule a follow-up appointment to discuss the results and determine the next steps if the IUI was unsuccessful.


Risks of IUI Pregnancy:

Though IUI is a relatively safe and non-invasive fertility treatment, there are a few risks associated with the procedure:

  • Multiple Pregnancies: IUI increases the chances of multiple pregnancies, particularly when combined with fertility medications that stimulate ovulation. While many couples view twins or triplets as a blessing, multiple pregnancies can increase the risk of complications, such as preterm labour and low birth weight.
  • Infection: There is a small risk of infection during the IUI procedure due to the insertion of the catheter through the cervix. However, this risk is minimal, and most clinics take strict precautions to ensure a sterile environment.


What are the Side Effects of IUI Pregnancy?

Some common side effects associated with IUI pregnancy include:

  • Mild cramping or discomfort following the procedure
  • Light spotting or bleeding due to the catheter’s insertion
  • Ovarian hyperstimulation syndrome (OHSS) in cases where fertility drugs are used, causing swollen, painful ovaries

It’s essential to consult your doctor if you experience severe pain, heavy bleeding, or other concerning symptoms.


Benefits of IUI:

Despite the potential risks and side effects, IUI offers numerous benefits for couples seeking fertility treatment:

  • Minimally Invasive: IUI is a non-surgical and minimally invasive fertility treatment, requiring only a thin catheter to insert sperm into the uterus. This makes it a more accessible option for many couples compared to more invasive treatments like in vitro fertilization (IVF).
  • Cost-Effective: IUI is generally more affordable than other fertility treatments, making it an appealing choice for couples on a budget.
  • Increased Chance of Conception: By bypassing the cervix and placing sperm directly into the uterus, IUI increases the chances of sperm reaching the fallopian tubes and fertilizing an egg.


The Success Rate of IUI in India:

IUI success rates vary depending on several factors, including age, overall health, and the underlying cause of infertility. In India, the success rate of IUI ranges from 10% to 20% per cycle, which is comparable to global success rates. It’s important to note that the likelihood of success may improve with multiple IUI cycles.


Keys to a Successful IUI Pregnancy:

To increase your chances of a successful IUI pregnancy, consider the following tips:

  • Maintain a Healthy Lifestyle: Adopting a healthy lifestyle can improve fertility and increase the chances of IUI success. This includes regularly eating a balanced diet, exercising by routine, managing stress, and avoiding smoking & excessive alcohol consumption.
  • Follow Your Doctor’s Recommendations: Your fertility specialist may prescribe medications or provide specific instructions to optimize your IUI success. Adhering to these recommendations is crucial for achieving the best possible outcome.
  • Choose a Reputable Clinic: Selecting a reputable fertility clinic with experienced doctors and high success rates can significantly impact your IUI experience and success.


Priya’s IUI Experience at Little Angel IVF:

To add a human touch to our discussion, let’s share Priya’s IUI journey. Priya and her husband struggled with infertility for three years before considering IUI. Despite her apprehensions about the procedure and its success, Priya was relieved to find the process minimally invasive and relatively pain-free.

After two cycles of IUI and diligently following Dr Mona’s recommendations, Priya and her husband were overjoyed to discover they were expecting their first child. Throughout her IUI journey, Priya focused on maintaining a healthy lifestyle, managing her stress, and staying positive.

Her experience highlights the importance of selecting a reputable clinic, adhering to a doctor’s guidance, and adopting a holistic approach to optimize the chances of a successful IUI pregnancy.


IUI is an accessible and cost-effective fertility treatment option for couples in India. By understanding the process, managing expectations, and taking proactive steps to improve the chances of success, couples can embark on their IUI journey with confidence and hope. The personal stories of individuals like Priya demonstrate that, with perseverance and the right support, IUI can indeed be a life-changing experience.



Q: How quickly do you get pregnant with IUI?

A: The success of IUI largely depends on various factors such as the age of the woman, the reason for infertility, and sperm quality. Generally, couples may require multiple cycles of IUI before getting pregnant. However, many people conceive within the first few cycles of IUI treatment.

Q: Is IUI 100% successful?

A: No, IUI is not 100% successful. The success rate of IUI depends on various factors such as the age of the woman, the reason for infertility, and the sperm quality. The success rate of IUI varies between 10% to 20% per cycle.

Q: Can you get pregnant on your first IUI?

A: Yes, it is possible to get pregnant on the first IUI cycle. However, the success rate varies depending on several factors such as the age of the woman, the reason for infertility, and the sperm quality.

Q: What is an IUI pregnancy?

A: An IUI pregnancy is a pregnancy that results from intrauterine insemination (IUI) treatment. During IUI, sperm is placed directly into the uterus, which increases the chances of fertilization and pregnancy.

Q: What is the success rate of IUI on the first try?

A: The success rate of IUI on the first try varies depending on several factors such as the age of the woman, the reason for infertility, and the sperm quality. However, on average, the success rate of IUI on the first try is between 10% to 20%.

Q: Is twins possible in IUI?

A: Yes, twins are possible in IUI. The use of fertility drugs to stimulate ovulation may increase the chances of having twins or multiples.

Q: What is the total cost of IUI?

A: The cost of IUI varies depending on several factors such as the location, the clinic, and the type of insurance coverage. On average, the total cost of IUI can range from $500 to $4,000 per cycle.

Q: What is the cost of IUI in India?

A: The cost of IUI in India varies depending on several factors such as the location, the clinic, and the type of treatment required. On average, the cost of IUI in India can range from INR 10,000 to INR 20,000 per cycle.

Q: What is the best sperm for IUI?

A: The best sperm for IUI is motile and has good morphology. A sperm count of at least 10 million motile sperm is considered optimal for IUI. In some cases, sperm washing may be required to remove any impurities and improve the quality of the sperm for IUI.

Q: Is it OK to travel after IUI?

A: Yes, it is generally safe to travel after IUI. However, it is recommended to avoid any strenuous activities, such as heavy lifting, that may increase the risk of complications.

Q: What are the disadvantages of IUI?

A: Some of the disadvantages of IUI include the risk of infection, multiple pregnancies, and the potential for the procedure to be unsuccessful. Additionally, the use of fertility drugs may increase the risk of ovarian hyperstimulation syndrome (OHSS).

Q: Is one egg good for IUI?

A: Yes, one egg can be sufficient for IUI. However, the chances of success may increase with multiple eggs, which can be achieved through the use of fertility drugs to stimulate ovulation.

Q: How painful is an IUI?

A: IUI is usually not very painful and is often described as similar to a pap smear. Some of the women may experience mild cramping sometimes or discomfort during the procedure.

Q: Who benefits from IUI?

A: IUI may benefit couples with unexplained infertility, mild male factor infertility, or cervical mucus problems. Additionally, IUI may be recommended for same-sex couples or individuals using donor sperm.

Q: What are the two types of IUI?

A: The two types of IUI are natural cycle IUI and medicated IUI. In natural cycle IUI, ovulation is monitored, and sperm is placed directly into the uterus during the woman’s natural ovulation cycle. In medicated IUI, fertility drugs are used to stimulate ovulation before the procedure.

Q: How long does it take for sperm to reach egg in IUI?

A: Sperm can reach the egg within 30 minutes to 12 hours after the procedure, depending on the quality and motility of the sperm.

Q: Is the day of IUI considered day 1?

A: No, the day of IUI is not considered day 1 of pregnancy. The day of IUI is typically considered day 0 or the day of insemination.

Q: How long does it take to get sperm for IUI?

A: The process of obtaining sperm for IUI can take anywhere from a few hours to several days, depending on the method used. Fresh sperm can be obtained on the same day as the procedure, while frozen sperm may need to be thawed and prepared in advance.

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    Dr Mona Dahiya

    Dr Mona Dahiya

    IVF Specialist & Consultant

    Dr Mona Dahiya has performed over 5,000+ IVF cycles and is considered a global expert in IVF, ICSI, IUI and male fertility treatment. She is an eminent writer on Infertility Treatment and has over 100 Publications in both International and National Journals. Dr Mona Dahiya has immensely contributed to the field of infertility through her Research and articles.

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