IVF with Donor Eggs : Process & Success Rate

by | Jan 26, 2023 | IVF

What is IVF?

In Vitro Fertilization (IVF) is a form of assisted reproductive technology (ART) that involves fertilizing an egg with sperm outside of the body. The process is usually recommended for couples who are unable to conceive through traditional methods, such as having sexual intercourse.

In Vitro Fertilization (IVF)

In Vitro Fertilization (IVF)

IVF is typically a multi-step process that involves the use of fertility drugs to stimulate the ovaries to produce multiple eggs, which are then retrieved through a minor surgical procedure. The eggs are then fertilized with sperm in a laboratory dish, and the resulting embryos are monitored for several days before being transferred back into the uterus. Now Let’s understand IVF with Donor Egg.

 

What is IVF with Donor Eggs?

IVF with donor eggs is a variation of the procedure that involves using eggs from a donor instead of the intended mother. This approach is typically recommended for women who are unable to produce viable eggs due to age, genetic disorders, or other medical conditions.

The process of finding an egg donor typically involves working with a fertility clinic or agency that specializes in matching donors with recipients. The donor may be a known individual, such as a family member or friend, or an anonymous donor recruited through an agency.

Also Read: How Much Does Surrogacy Cost in India?

Where to Find an Egg Donor?

In general, there are two types of egg donors: anonymous and known. Anonymous donors are individuals who have agreed to donate their eggs to a fertility clinic or agency without disclosing their identity to the recipient. Known donors, on the other hand, are individuals who are known to the recipient, such as a family member or friend.

When selecting an egg donor, there are several factors to consider, including the donor’s age, medical history, physical characteristics, and genetic background. Donors are typically screened for a range of medical and genetic conditions to ensure that they are healthy and suitable candidates.

Once a donor has been selected, the IVF process can begin. The recipient will typically undergo a series of fertility treatments to prepare her uterus for embryo transfer. Meanwhile, the donor will undergo a series of hormone injections to stimulate her ovaries to produce multiple eggs. The eggs will then be retrieved through a minor surgical procedure and fertilized with the intended father’s sperm.

After fertilization, the resulting embryos will be monitored for several days before being transferred back into the recipient’s uterus. Depending on the quality and number of embryos, additional embryos may be frozen for future use.

Overall, IVF with donor eggs is a highly effective form of assisted reproductive technology that has helped many couples overcome infertility and achieve their dream of having a child. However, it is important to carefully consider all of the factors involved and work with a reputable clinic or agency to ensure the best possible outcome.

 

When Does IVF with Donor Eggs is Recommended?

IVF with Donor Eggs is recommended in the following 5 Cases.

  1. Women with Low Ovarian Reserve i.e., Count of Eggs.
  2. Women With Low- or Poor-Quality Eggs.
  3. Absence of Ovaries or Genetic Disorders.
  4. Ovarian Failure Due to Ailments Like Cancer Treatment.
  5. Women Trying to Conceive in ’40s.

IVF with Donor Egg Step by Step Process:

1. PATIENT CONSULTATION:

Couples with 2/3 Failed Natural IVF Cycles in the past are generally recommended IVF With Donor Eggs. The objective of the Consultation is to gauge past Medical History and counsel patients on the process, Timelines, Cost, Donor selection and the subsequent transfer of Fertilized Embryos. Consent Forms are signed as per Legal & Confidential requirements.

2. PATIENT TESTS:

Three Essential Tests i.e., Uterine Sounding, Semen Analysis & Blood Tests are done to ascertain a simulated Embryo Transfer apart from diagnosing any Genetic/Medical Disorders. If the Tests indicate, Fibroid or Polyps then a Hysteroscopy may be recommended. Certain additional Tests like mammograms may be recommended to check for Blocked Fallopian Tubes.

3. DONOR PROFILING & MATCHING:

All Donors are screened for Physical Characteristics, Complexion, Blood Type & Medical History based on Patient Consultation. It has to be noted that, all Donor Egg Profiling & Selection is Anonymous & Confidential. Donor Matching is done based on the information supplied by the recipient and Donor screening. Donor’s Identity is never disclosed to the Patient and Vice-versa.

4. DONOR SCREENING & SELECTION:

A Donor has to be in the age group of 21-29 Years and come to any of our IVF Clinics in India for Screening. A detailed Medical, Educational & Family history is taken from all Donors as part of the selection process. All Potential Donors have to mandatory undergo Hormonal Tests, Blood Tests and Cultures Tests for Sexually Transmitted Diseases, Alcohol and Tobacco Consumption and Drug Abuse. After a rigorous screening process is completed, an informed decision is made to proceed with a donor. All Egg Donors have to sign a confidentiality agreement with no association or claims to any Child born out of Egg Donation.

5. OVARIAN STIMULATION OF DONOR:

Once a Donor is selected, she is given certain medicated Drugs like Lupron, Estrogen, Progesterone & Gonadotropins for what is known as controlled ovarian hyperstimulation to produce an optimal number of Eggs. Once the Ovaries have been stimulated, a donor has to strictly abstain from sexual intercourse as the Ovaries are Fertile.

6. MONITORING DONOR:

The Donor is Monitored at regular intervals through Ultrasound Tests & Blood Tests to determine Follicle Development. Certain Medications may be given 24-48 Hours before the Date of Egg Retrieval.

7. EGG RETRIEVAL:

A Donor is prescribed not to Eat or Drink after Midnight before the Day of Egg retrieval. Eggs are retrieved Vaginally through an Ultrasound Probe with a Needle to aspirate the Follicles. The Procedure usually lasts for about 20 minutes and the Donor is recommended rest for 1 Hour post the Egg retrieval.

8. EGG FERTILIZATION:

Donor Eggs and Male Sperm collected from the Husband are cultured and checked before fertilization. The Embryologist will then pursue the Fertilization process in a Laboratory to develop Embryos.

9. EMBRYO TRANSFER:

Embryo Transfer is usually done 2/3 Days after Egg Fertilization. The process of Embryo Transfer is Painless and done under Anaesthesia. Embryos are gently transferred through a Catheter into the Uterus of the Patient under Ultrasound. After the transfer, a patient is recommended 2 Hours of rest at all of our IVF Clinics in India and recommended 2 Days of Bed rest post-discharge.

Success Rate of IVF with Donor Eggs:

The success rate of IVF with donor eggs can vary depending on a range of factors, including the age and health of the recipient, the quality of the donor eggs, and the expertise of the fertility clinic or agency.

Overall, IVF with donor eggs has a higher success rate than traditional IVF, particularly for women over the age of 40. According to the Centers for Disease Control and Prevention (CDC), the live birth rate for IVF with donor eggs was 56.6% per embryo transfer in 2019. However, success rates can vary widely between clinics and individual cases, so it is important to discuss expectations and outcomes with a fertility specialist.

Side Effects/ Risks of IVF with Donor Eggs:

Like all medical procedures, the Risks of IVF with donor eggs can include:

  • Ovarian hyperstimulation syndrome (OHSS): This is a condition that can occur when the ovaries are stimulated too much during the egg retrieval process. Symptoms can include abdominal pain, bloating, and nausea.
  • Multiple pregnancies: Because multiple embryos are often transferred during IVF, there is a higher risk of having multiple pregnancies, which can increase the risk of complications such as premature delivery.
  • Emotional side effects: IVF can be a stressful and emotional process, particularly for couples who have struggled with infertility. It is important to seek support and counselling as needed to manage these feelings.
  • Infection: There is a small risk of infection associated with any surgical procedure, including the egg retrieval process.

 

Cost of IVF with Donor Eggs:

The cost of IVF with donor eggs can vary widely depending on a range of factors, including the location of the clinic or agency, the quality of the donor eggs, and the number of cycles required.

In general, IVF with donor eggs is more expensive than traditional IVF, with costs typically ranging from ₹ 1,50,000 to ₹ 2,50,000 per cycle. This cost typically includes the cost of the donor eggs, fertility medications, and the IVF procedure itself.

However, some insurance plans may cover some or all of the costs associated with IVF with donor eggs, so it is important to check with your insurance provider to understand what is covered.

In addition, some clinics and agencies may offer financing options or payment plans to help make the cost more manageable.

In summary, IVF with donor eggs can be a highly effective form of assisted reproductive technology for couples struggling with infertility. While there are some risks and potential side effects associated with the procedure, the high success rates and the possibility of achieving a long-awaited pregnancy often make it a viable option for many. However, it is important to carefully consider all of the factors involved, including the cost and potential emotional impact, before making a decision. Working with a reputable clinic or agency and seeking support and counselling as needed can help ensure the best possible outcome.

Also Read: IVF Cost in India

 

WHAT HAPPENS AFTER EMBRYO TRANSFER?

Dr Mona Dahiya will recommend Pregnancy Tests & Blood Tests as per prescribed timelines after the Embryo Transfer is done. Our Staff at Little Angel IVF will provide a Consultation and Diet Chart to give you clarity on the next steps to welcome your Little one.

Also Read: IVF Cost in Delhi

FAQs:

Q: Is IVF successful with donor eggs?

A: IVF with donor eggs can be highly successful, with a live birth rate of around 56.6% per embryo transfer according to the CDC. Success rates can vary depending on factors such as the health of the recipient and the quality of the donor eggs.

Q: What are the disadvantages of donor egg in IVF?

A: The disadvantages of donor egg IVF can include emotional and psychological challenges, as well as potential side effects and risks such as ovarian hyperstimulation syndrome and multiple pregnancies.

Q: What are the chances of pregnancy with donor eggs?

A: The chances of pregnancy with donor eggs can be high, with success rates varying depending on factors such as the health of the recipient and the quality of the donor eggs. According to the CDC, the live birth rate for IVF with donor eggs was around 56.6% per embryo transfer in 2019.

Q: Is a donor egg still your baby?

A: While the genetics of the child may come from a donor, the child is still considered your baby if you are carrying and raising them.

Q: Will my baby look like me if I use a donor egg?

A: Since the child will not have the genetic material from the recipient, they will not resemble the recipient biologically. However, there are still many ways that the child can bond with and resemble the recipient through nurturing and environmental factors.

Q: Do celebrities use donor eggs?

A: While it is difficult to know for sure which celebrities have used donor eggs or other forms of assisted reproductive technology, it is known that some have discussed their struggles with fertility and the use of these methods.

Q: What is the maximum age for IVF with donor egg?

A: The maximum age for IVF with donor egg can vary depending on the individual case and the fertility clinic or agency. In general, women over the age of 50 may not be eligible for donor egg IVF due to the increased risks associated with pregnancy at that age.

Q: Are donor eggs a good idea?

A: For couples struggling with infertility, donor eggs can be a highly effective form of assisted reproductive technology. However, it is important to carefully consider all of the factors involved, including the emotional impact and the cost, before making a decision.

Q: Can your body reject a donor embryo?

A: In general, the risk of the recipient’s body rejecting a donor embryo is low. However, there is a small risk of rejection or other complications associated with any form of transplantation.

Q: How much does donor egg cost in India?

A: The cost of donor egg IVF in India can vary depending on a range of factors, including the clinic or agency, the quality of the donor eggs, and the number of cycles required. In general, costs can range from around $5,000 to $15,000 per cycle.

Q: Why does donor egg IVF fail?

A: Donor egg IVF can fail for a range of reasons, including implantation failure, genetic abnormalities in the embryos, and other medical complicatio

Q. What is The Success Rate Of IVF With Donor Eggs in India?

A. To find an egg donor for IVF in India, you can consider searching for egg donor clinics or IVF centers that provide donor egg services. Many clinics have a database of donors and you can choose a donor based on certain criteria such as age, physical characteristics, medical history, etc.The success rates of IVF with donor eggs can vary greatly and are influenced by several factors such as the age of the recipient, the quality of the embryos, and the experience of the clinic. The success rate of IVF with donor eggs can range from 40-60% per cycle, but this can vary based on the individual case. It is important to discuss the success rates of IVF with donor eggs with your doctor to understand the chances of success for your specific case.

Q. Where to Find an Egg Donor for IVF?

A. To find an egg donor for IVF in India, you can consider searching for egg donor clinics or IVF centers that provide donor egg services. Many clinics have a database of donors and you can choose a donor based on certain criteria such as age, physical characteristics, medical history, etc.

Q. Risks Of IVF With Donor Eggs?

A.The risks associated with IVF with donor eggs include:

  • Ovarian Hyperstimulation Syndrome (OHSS): This is a condition where the ovaries become swollen and painful due to the stimulation of ovaries to produce eggs.
  • Multiple pregnancies: IVF with donor eggs increases the likelihood of multiple pregnancies, which can pose risks to both the mother and the fetuses.
  • Ectopic pregnancy: This is a condition where the fertilized egg implants itself outside the uterus, which can be dangerous for the mother.
  • Infection: There is a risk of infection associated with the procedure of retrieving the eggs from the donor.
  • Rejection of the embryos: In some cases, the recipient’s body may reject the embryos, leading to a failed IVF cycle.

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    Dr Mona Dahiya

    Dr Mona Dahiya

    IVF Specialist & Consultant

    Dr Mona Dahiya has performed over 5,000+ IVF cycles and is considered a global expert in IVF, ICSI, IUI and male fertility treatment. She is an eminent writer on Infertility Treatment and has over 100 Publications in both International and National Journals. Dr Mona Dahiya has immensely contributed to the field of infertility through her Research and articles.

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